In a joint project with life sciences, we investigate the communications and code properties of the DNA. Our share deals with reasoning of the codon/aminoacid encoding structure, the error-protection, and source coding properties, whereas Prof. Mushelishvili’s group concentrates more on the influences of the three dimensional orientation leading to analog control mechanisms in gene expression.


  • Journal Articles

    Nigatu, Dawit; Sobetzko, Patrick; Yousef, Malik; Henkel, Werner

    Sequence-based Information-theoretic Features for Gene Essentiality Prediction Journal Article

    BMC Bioinformatics, 18 (473), 2017.

    Links | BibTeX

    Yousef, Malik; Nigatu, Dawit; Levy, Dalit; Allmer, Jens; Henkel, Werner

    Categorization of Species based on their MicroRNAs Employing Sequence Motifs, Information-Theoretic Sequence Feature Extraction, and k-mers Journal Article

    EURASIP Journal on Advances in Signal Processing, 2017.

    Links | BibTeX

    Nigatu, Dawit; Henkel, Werner; Sobetzko, Patrick; Muskhelishvili, Georgi

    Relationship between Digital Information and Thermodynamic Stability in Bacterial Genomes Journal Article

    EURASIP Journal on Bioinformatics and Systems Biology, 4 , 2016.

    Abstract | Links | BibTeX

    Nigatu, Dawit; Mahmood, Attiya; Henkel, Werner

    The Empirical Codon Mutation Matrix as a Communication Channel Journal Article

    BMC Bioinformatics, 15 (80), 2014.

    Abstract | Links | BibTeX


    Henkel, Werner; Nigatu, Dawit A; Islam, Nazia; Mahmood, Attiya

    Some results from a joint project on Information Theory and Genetics Workshop

    ECE Graduate Seminar, Old Dominion University, Norfolk, VA, 2015.

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    Mahmood, Attiya; Henkel, Werner

    Codon Based Distance Matrix using Modified Empirical Codon Mutation Matrix Workshop

    Meeting on Gene Regulation and Information Theory, ITG-Fachgruppe "Bio-Informationstheorie", Halle, Germany, 2013.

    Links | BibTeX

    Book Chapters

    Nigatu, Dawit; Henkel, Werner

    Computational Identification of Essential Genes in Prokaryotes and Eukaryotes Book Chapter

    Peixoto, Nathalia; Silveira, Margarida; Al, Hesham H; Maciel, Carlos; van den Broek, Egon L (Ed.): 881 , pp. 227-247, Springer, Cham, 2018, ISBN: 978-3-319-94806-5, 978-3-319-94805-8.

    Links | BibTeX

    Henkel, Werner; Muskhelishvili, Georgi; Nigatu, Dawit; Sobetzko, Patrick

    The DNA from a Coding Perspective Book Chapter

    Bossert, Martin (Ed.): Springer Lecture Notes in Bioengineering: Information- and Communication Theory in Molecular Biology, 2017, ISBN: 978-3-319-54729-9, 978-3-319-54728-2.

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    Henkel, Werner ; Mehmood, Attiya; Islam, Nazia

    Verfahren zur Kompression von Quelldaten unter Nutzung von Symmetrien und Einrichtung zur Durchführung des Verfahrens Patent

    PCT/EP2014/050381 2014.

    Links | BibTeX

    Ph.D. Theses

    Nigatu, Dawit

    The DNA from a Communications and Information Theoretic Perspective Ph.D. Thesis


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    In Proceedings

    Nigatu, Dawit Andualem; Henkel, Werner

    Multilevel capacities for the codon mutation channel In Proceeding

    10th International Symposium on Turbo Codes & Iterative Information Processing (ISTC 18) Hong Kong, 2018.

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    Nigatu, Dawit; Henkel, Werner

    Prediction of Essential Genes Based on Machine Learning and Information Theoretic Features In Proceeding

    8th International Conference on Bioinformatics Models, Methods and Algorithms, Porto, 2017.

    Abstract | Links | BibTeX

    Nigatu, Dawit A; Henkel, Werner; Sobetzko, Patrick; Muskhelishvili, Georgi

    Relating Digital Information, Thermodynamic Stability, and Classes of Functional Genes in E. coli In Proceeding

    IEEE GlobalSIP14-Workshop on Genomic Signal Processing and Statistics 2014, Atlanta, Georgia, USA, 2014.

    Links | BibTeX

    Mahmood, Attiya; Islam, Nazia; Nigatu, Dawit; Henkel, Werner

    Bi-directional Lempel-Ziv-like Compression Algorithms in the DNA and its Technical Counterpart In Proceeding

    IEEE 2014 8th International Symposium on Turbo Codes and Iterative Information Processing (ISTC), 2014.

    Links | BibTeX